Cyclopamine tartrate for cell activation
Catalog number
2518-1
Name
Cyclopamine tartrate for cell activation
Size
1 mg
Price
153.00 EUR
Supplier
Details
Description
Cyclopamine tartrate is a water-soluble derivative of the Hedgehog (Hh) signaling pathway inhibitor Cyclopamine (Cyc) (Cat. No.1578). Displays higher inhibitory activity for Hh signaling-dependent motor neuron differentiation than did Cyc (IC₀ = 50 nmol/L for CycT vs. 300 nmol/L for Cyc). CycT-treated mice shows tumor shrinkage and decreased expression of Hh target genes.
Peptide sequence
N/A
CAS number
1178510-81-0
Molecular weight
973.32
Category
Biochemicals
Other name
(2'R,3S,3'R,3'aS,6'S,6aS,6bS,7'aR,11aS,11bR)-1,2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11,11a,11b-Octadecahydro-3',6',10,11b-tetramethylspiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-3-ol tartrate; 11-Deoxojervine Tartrate; (3β,23β)-17,23-Epoxy- veratraman-3-ol Tartrate; 11-Deoxyjervine Tartrate; CycT
Molecular formula
C₅₈H₈₈N₂O₁₀
Physical appearance
Crystalline solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
No
Purification
≥98%
Reconstitute instructions
H₂O (~2 mg/ml)
Storage condition
-20°C
Shipping condition
Gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
