Kaempferol for cell activation

A naturally occurring polyphenol antioxidant that displays a wide range of pharmacological activities, including antioxidant, anti-inflammatory, antimicrobial, anticancer, cardioprotective, neuroprotective, antidiabetic, anti-osteoporotic, estrogenic/antiestrogenic, anxiolytic, analgesic and antiallergic activities. It reduces cell cycle progression in HT-29 cells. Kaempferol increases chromatin condensation, DNA fragmentation and the number of early apoptotic cells in HT-29 cells in a dose-dependent manner. In addition, kaempferol increases the levels of cleaved caspase-9, caspase-3 and caspase-7 as well as those of cleaved poly (ADP-ribose) polymerase. Moreover, it increases mitochondrial membrane permeability and cytosolic cytochrome c concentrations.

N/A

520-18-3

286.24

Biochemicals

3,4′,5,7-Tetrahydroxyflavone, 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, Robigenin

C₁₅H₁₀O₆

Yellow solid

N/A

No

Yes

≥95% by HPLC

DMSO (25 mg/ml) or EtOH (20 mg/ml)

-20°C

Gel pack

24 months

Protect from air and light

cell

For cells, cell lines and tissues in culture till half confluency.