EZSolution™ GDC-0449 for cell activation
Catalog number
2539-5
Name
EZSolution™ GDC-0449 for cell activation
Size
5 mg
Price
197.00 EUR
Supplier
Details
Description
A potent inhibitor of Smoothened (SMO), a key mediator of Hedgehog (Hh) signaling pathway. Inhibition of SMO renders the transcription factor GLI inactive, thus preventing the expression of genes that mediate the role of Hh on tumor growth.
Peptide sequence
N/A
CAS number
879085-55-9
Molecular weight
421.3
Category
Biochemicals
Other name
2-Chloro-N-(4-chloro-3-(pyridine-2-yl)phenyl)-4-(methylsulfonyl)benzamide; HhAntag691
Molecular formula
C₁₉H₁₄Cl₂N₂O₃S
Physical appearance
Liquid
Supplied with
A 10 mM solution in anhydrous DMSO
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
N/A
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
12 months
Storage instructions
Protect from air and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
