EZSolution™ Cyclopamine for cell activation
Catalog number
2545-5
Name
EZSolution™ Cyclopamine for cell activation
Size
5 mg
Price
273.00 EUR
Supplier
Details
Description
Cyclopamine blocks activation of the Hedgehog response pathway associated with mutations that either activate the proto-oncogene Smoothened (Smo) or inactivate the tumour suppressor Patched (Ptch) both of which encode multipass transmembrane proteins. Furthermore, it has been demonstrated that the inhibitory effect of cyclopamine results from its direct binding to the Smo heptahelical protein bundle
Peptide sequence
N/A
CAS number
4449-51-8
Molecular weight
411.62
Category
Biochemicals
Other name
11-deoxojervine
Molecular formula
C₂₇H₄₁NO₂
Physical appearance
Liquid
Supplied with
A 10 mM solution in anhydrous DMSO
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥99%
Reconstitute instructions
N/A
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
12 months
Storage instructions
Protect from moisture and air
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
