EZSolution™ GW2580 for cell activation
Catalog number
2549-5
Name
EZSolution™ GW2580 for cell activation
Size
5 mg
Price
142.00 EUR
Supplier
Details
Description
A small-molecule, ATP-competitive inhibitor of cFMS kinase; at 60 nM it inhibits human cFMS kinase completely in vitro and was inactive against 26 other kinases. GW2580 also inhibits lipopolysaccharide (LPS)-induced TNF production in mice, but not LPS-induced TNF production in freshly isolated human monocytes and mouse macrophages in vitro.
Peptide sequence
N/A
CAS number
870483-87-7
Molecular weight
366.41
Category
Biochemicals
Other name
5-(3-Methoxy-4-((4-methoxybenzyl)oxy)benzyl)pyrimidine-2,4-diamine
Molecular formula
C₂₀H₂₂N₄O₃
Physical appearance
Liquid
Supplied with
A 10 mM solution in anhydrous DMSO
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥99% by HPLC
Reconstitute instructions
N/A
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
12 months
Storage instructions
Protect from air and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
