Human CellExp™ BCMA / TNFRSF17, human recombinant

Catalog number

P1074-50

Size

50 µg

Price

529.00 EUR

Supplier

Biovision

Order

Details

Target

CD269

Background

Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily. TNFRSF17 contains one TNFR-Cys repeat. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity. TNFRSF17 can activate NF-kappa-B and JNK.

Concentration

N/A

Molecular weight

7.5 kDa

Synonym

TNFRSF17, CD269, BCM, BCMA

Other name

TNFRSF17, CD269, BCM, BCMA

NCBI gene number

608

NCBI gene

TNR17

Gene source

Human

NCBI number

Q02223

Recombinant

Yes

Source

HEK 293 cells

Purification

≥90%

Tested applications

SDS-PAGE, N/A

Level of endotoxin

< 1 EU/μg

Tested activity

Measured by its binding ability in a functional ELISA.

Biological activity

Immobilized Human BCMA, His Tag at 5 μg/mL (100 μL/well) can bind Biotinylated Human BAFF with a linear range of 0.24-3.9 ng/mL.

Reesults

N/A

Binding ability

Immobilized Human BCMA, His Tag at 5 μg/mL (100 μL/well) can bind Biotinylated Human BAFF with a linear range of 0.24-3.9 ng/mL.

Unit

N/A

Storage condition

-20°C

Shipping under

Gel pack

Physical appearance

Lyophilized

Physical properties

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Generally Mannitol or Trehalose is added as a protectant before lyophilization.

How to reconstitute

Reconstitute in sterile deionized water to a concentration of 50 μg/ml.

Aa sequence

N/A

Before use

Centrifuge the vial prior to opening.

Notes

For Research Use Only! Not to be used in humans

Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

Additional source

Recombinants or rec. proteins

Group

recombinants