AMG-208 for cell activation
Catalog number
2553-25
Name
AMG-208 for cell activation
Size
25 mg
Price
757.00 EUR
Supplier
Details
Description
AMG-708 is a selective small-molecule inhibitor (IC₅₀ = 9.3 nM) of the proto-oncogene c-Met with potential antineoplastic activity. AMG 208 inhibits the ligand-dependent and ligand-independent activation of c-Met, inhibiting its tyrosine kinase activity, which may result in cell growth inhibition in tumors that overexpress c-Met.
Peptide sequence
N/A
CAS number
1002304-34-8
Molecular weight
383.4
Category
Biochemicals
Other name
7-methoxy-4-((6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy)quinoline
Molecular formula
C₂₂H₁₇N₅O₂
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (~ 1 mg in ml) or EtOH (~ 1 mg/ml)
Storage condition
-20°C
Shipping condition
Gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
