SGI-1776 for cell activation
Catalog number
2554-25
Name
SGI-1776 for cell activation
Size
25 mg
Price
675.00 EUR
Supplier
Details
Description
SGI-1776 is a potent and ATP-competitive Pim kinase inhibitor (IC₅₀’s = 7, 363, and 69 nM for Pim-1, Pim-2 and Pim-3, respectively). SGI-1776 also inhibits FLT3 (IC₅₀ = 44 nM). Induces apoptosis in chronic lymphocytic leukemia cells.
Peptide sequence
N/A
CAS number
1025065-69-3
Molecular weight
405.42
Category
Biochemicals
Other name
N-[(1-Methyl-4-piperidinyl)methyl]-3-[3-(trifluoromethoxy)phenyl]imidazo[1,2-b]pyridazin-6-amine
Molecular formula
C₂₀H₂₂F₃N₅O
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (>75 mg/ml)
Storage condition
-20°C
Shipping condition
Gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
