Evacetrapib for cell activation

Catalog number

2558-5

Size

5 mg

Price

251.00 EUR

Supplier

Biovision

Order

Details

Description

Evacetrapib is a potent, and selective CETP (cholesteryl ester transfer protein) inhibitor. It inhibits human recombinant CETP protein (IC₅₀ = 5.5 nM ) and CETP activity in human plasma (IC₅₀ = 36 nM) in vitro. Unlike Torcetrapib (Cat. No. 2420 & 2533), Evacetrapib does not induce aldosterone or cortisol biosynthesis.

Peptide sequence

N/A

CAS number

1186486-62-3

Molecular weight

638.65

Category

Biochemicals

Other name

trans-4-[[(5S)-5-[[[3,5-bis(trifluoromethyl)phenyl]methyl](2-methyl-2H-tetrazol-5-yl)amino]-2,3,4,5-tetrahydro-7,9-dimethyl-1H-1-benzazepin-1-yl]methyl]- cyclohexanecarboxylic acid; LY2484595

Molecular formula

C₃₁H₃₆F₆N₆O₂

Physical appearance

Crystalline solid

Supplied with

N/A

Is this a salt?

Is it cell-permeable?

Yes

Purification

≥95% by HPLC

Reconstitute instructions