Cilostamide for cell activation
Catalog number
2560-5
Name
Cilostamide for cell activation
Size
5 mg
Price
186.00 EUR
Supplier
Details
Description
A selective type III phosphodiesterase-3 (PDE3) inhibitor. Displays limited selectivity for PDE3A versus PDE3B (IC₅₀ = 27 and 50 nM). This inhibitory effect increases intracellular cAMP and inhibits platelet aggregation. Cilostamide also blocks PKB/Akt signaling pathway downstream via inhibition of Akt-activated PDE3B.
Peptide sequence
N/A
CAS number
68550-75-4
Molecular weight
342.44
Category
Biochemicals
Other name
N-Cyclohexyl-N-methyl-4-(1,2-dihydro-2-oxo-6-quinolyloxy)butyramide
Molecular formula
C₂₀H₂₆N₂O₃
Physical appearance
White solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (~30 mg/ml)
Storage condition
-20°C
Shipping condition
Gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
