MMP-III Inhibitor, NNGH for cell activation

Catalog number
2569-5
Name
MMP-III Inhibitor, NNGH for cell activation
Size
5 mg
Price
153.00 EUR
Supplier

Details

Description
Cell-permeable. A potent inhibitor of matrix metalloproteinase-3 (MMP-3)( Ki = 0.013 µM). Also inhibits MMP-1, -2, -7-10, -12-14 and MMP-20. Attenuates inflammation-induced thermal hyperalgesia.
Peptide sequence
N/A
CAS number
161314-17-6
Molecular weight
316.38
Category
Biochemicals
Other name
N-Isobutyl-N-(4-methoxyphenylsulfonyl)glycyl hydroxamic acid
Molecular formula
C₁₃H₂₀N₂O₅S
Physical appearance
White solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
³98% by TLC
Reconstitute instructions
DMSO (~25 mg/ml) or EtOH (~ 25 mg/ml
Storage condition
-20°C
Shipping condition
Gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.