NDGA for cell activation
Catalog number
2581-500
Name
NDGA for cell activation
Size
500 mg
Price
262.00 EUR
Supplier
Details
Description
NDGA is a a phenolic compound isolated from the creosote bush Larrea divaricatta that has anti-cancer activities both in vitro and in vivo. NDGA acts as a non-selective lipoxygenase (LO) inhibitor (IC₅₀ values are 3.0-5.0 µM for human platelet 12-LO and 0.91 µM for rabbit reticulocyte 15-LO). Also inhibits IGF-1 and c-erbB2/HER2/neu receptors and suppresses growth in breast cancer cells.
Peptide sequence
N/A
CAS number
500-38-9
Molecular weight
302.4
Category
Biochemicals
Other name
Nordihydroguaiaretic Acid; 4,4’-(2,3-dimethyl-1,4-butanediyl)bis-1,2-benzenediol
Molecular formula
C₁₈H₂₂O₄
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥97% by HPLC
Reconstitute instructions
DMSO (~100 mg/ml) or EtOH (~ 100 mg/ml)
Storage condition
-20°C
Shipping condition
Gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
