AT 56 for cell activation
Catalog number
2592-5
Name
AT 56 for cell activation
Size
5 mg
Price
229.00 EUR
Supplier
Details
Description
AT-56 is a selective, competitive, and highly bioavailable inhibitor of L-PGDS (lipocalin-type prostaglandin D synthase) (Ki = 75 µM). It inhibits the production of PGD2 by L-PGDS purified from human CSF and recombinant mouse cells with an IC₅₀ value of 95 µM. At concentrations as high as 100 µM in vitro or 30 mg/kg in vivo, AT-56 does not affect the production of PGE2, PGF2α, or H-PGDS-catalyzed PGD2.
Peptide sequence
N/A
CAS number
162640-98-4
Molecular weight
397.52
Category
Biochemicals
Other name
4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-[4-(2H-tetrazol-5-yl)butyl]-piperidine
Molecular formula
C₂₅H₂₇N₅
Physical appearance
White solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (>15 mg/ml)
Storage condition
-20°C
Shipping condition
Gel pack
Maximum time for storage
36 months
Storage instructions
Protect from light and air
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
