B-Raf Inhibitor 1 for cell activation
Catalog number
2599-5
Name
B-Raf Inhibitor 1 for cell activation
Size
5 mg
Price
186.00 EUR
Supplier
Details
Description
B-Raf inhibitor 1 is a potent and selective B-Raf inhibitor with cell IC₅₀s of 0.31 µM and 2 nM for A375 proliferation and A375 p-ERK respectively.
Peptide sequence
N/A
CAS number
1093100-40-3
Molecular weight
478.94
Category
Biochemicals
Other name
N1-(4-chlorophenyl)-6-methyl-N5-[3-(9H-purin-6-yl)-2-pyridinyl]- 1,5-Isoquinolinediamine
Molecular formula
C₂₆H₁₉ClN₈
Physical appearance
Crystalline solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
>98% by HPLC
Reconstitute instructions
DMSO
Storage condition
-20 ̊C
Shipping condition
Gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
