HG-10-012-01 for cell activation
Catalog number
2604-25
Name
HG-10-012-01 for cell activation
Size
25 mg
Price
577.00 EUR
Supplier
Details
Description
Brain-permeable. HG-10-102-01 is a potent and selective inhibitor of wild-type LRRK2 and the G2019S mutant (IC₅₀ values are ~20.3 nM and ~ 3.2 nM, respectively). It significantly inhibits Ser910 and Ser935 phosphorylation of both wild-type LRRK2 and G2019S mutant at a concentration of 0.1-0.3 µM in cells. May be a useful tool for Parkinson’s Disease research.
Peptide sequence
N/A
CAS number
1351758-81-0
Molecular weight
377.83
Category
Biochemicals
Other name
[4-[[5-Chloro-4-(methylamino)-2-pyrimidinyl]amino]-3-methoxyphenyl]-4-morpholinylmethanone
Molecular formula
C₁₇H₂₀ClN₅O₃
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
>98% by HPLC
Reconstitute instructions
DMSO (>30 mg/ml)
Storage condition
-20 ̊C
Shipping condition
Gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
