UNC0631 for cell activation
Catalog number
2605-5
Name
UNC0631 for cell activation
Size
5 mg
Price
186.00 EUR
Supplier
Details
Description
UNC0631 is a potent and selective inhibitor of G9a activity in vitro (IC₅₀ = 4 nM) and G9a/GLP-mediated dimethylation of histone 3 on lysine 9 in MDA-MB-231 cells (IC₅₀ = 25 nM). It potently inhibits G9a/GLP activity in a variety of cancer cell lines as well as in the human fetal lung IMR-90 cell line. Also displays excellent separation of functional potency versus cell toxicity.
Peptide sequence
N/A
CAS number
1320288-19-4
Molecular weight
635.93
Category
Biochemicals
Other name
[N-(1-(cyclohexylmethyl)piperidin-4-yl)-2-(4-isopropyl-1,4-diazepan-1-yl)-6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinazolin-4-amine
Molecular formula
C₃₇H₆₁N₇O₂
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
>98% by HPLC
Reconstitute instructions
DMSO (~30 mg/ml)
Storage condition
-20 ̊C
Shipping condition
Gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
