Xestospongin C for cell activation
Catalog number
2621-50
Name
Xestospongin C for cell activation
Size
50 µg
Price
697.00 EUR
Supplier
Details
Description
Xestospongin C is a marine natural product isolated from Pacific basin sponges; it antagonizes the calcium-releasing action of inositol-1,4,5-trisphosphate (IP3) at the receptor level. Xestospongin C blocks the increase in intracellular calcium in vascular smooth muscle cells completely at a concentration of 25 µM. Xe C also inhibits the sarcoplasmic reticulum Ca²⁺- ATPase pump at concentrations of 700 nM.
Peptide sequence
N/A
CAS number
88903-69-9
Molecular weight
446.71
Category
Biochemicals
Other name
(1R,4aR,11R,12aS,13S,16aS,23R,24aS)-Eicosahydro-5H,17H-1,23:11,13-diethano-2H,14H-[1,11]dioxacycloeicosino[2,3-b:12,13-b']dipyridine; XeC; Araguspongine E
Molecular formula
C₂₈H₅₀N₂O₂
Physical appearance
A clear film
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
>90%
Reconstitute instructions
DMSO (~ 2 mM) or EtOH (~ 2 mM)
Storage condition
-20 ̊C
Shipping condition
Gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
