STA-21 for cell activation
Catalog number
2626-1000
Name
STA-21 for cell activation
Size
1 mg
Price
567.00 EUR
Supplier
Details
Description
STA-21 is a natural antibiotic that acts as a selective STAT3 inhibitor. It inhibits STAT3 by preventing its dimerization and DNA binding when used at concentrations of 20-30 μM. It blocks the growth and survival of cancer cells that express constitutively active STAT3 (e.g., DU145 cells, IC₅₀ = 12.2 μM). It reciprocally regulates Th17 and Treg cells, and inhibits osteoclast formation.
Peptide sequence
N/A
CAS number
28882-53-3
Molecular weight
306.31
Category
Biochemicals
Other name
((3S)-3,4-dihydro-8-hydroxy-3-methyl-benz[a]anthracene-1,7,12(2H)-trione; Ochromycinone
Molecular formula
C₁₉H₁₄O₄
Physical appearance
Light orange solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
>98%
Reconstitute instructions
DMSO (~ 15 mg/ml)
Storage condition
-20 ̊C
Shipping condition
Gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
