GSK429286A for cell activation
Catalog number
2637-5
Name
GSK429286A for cell activation
Size
5 mg
Price
414.00 EUR
Supplier
Details
Description
GSK429286A is a potent and selective Rho-Kinase (ROCK) inhibitor (IC₅₀ = 14 and 63 nM for ROCK1 and ROCK2, respectively). ROCK inhibitors have been found to prevent apoptosis, as well as enhance the survival and cloning efficiency of dissociated human embryonic stem (ES) cells without affecting their self-renewal properties or pluripotency.
Peptide sequence
N/A
CAS number
864082-47-3
Molecular weight
432.27
Category
Biochemicals
Other name
4-[4-(Trifluoromethyl)phenyl]-N-(6-Fluoro-1H-indazol-5-yl)-2-methyl-6-oxo-1,4,5,6-tetrahydro-3-pyridinecarboxamide; GSK429286
Molecular formula
C₂₁H₁₆F₄N₄O₂
Physical appearance
White solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
>98% by HPLC
Reconstitute instructions
DMSO (~40 mg/ml) or EtOH (~10 mg/ml)
Storage condition
-20 ̊C
Shipping condition
Gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
