Pelitinib (EKB-569) for cell activation
Catalog number
2676-5
Name
Pelitinib (EKB-569) for cell activation
Size
5 mg
Price
132.00 EUR
Supplier
Details
Description
Pelitinib is a pan-ErbB tyrosine kinase inhibitor with potential anticancer activity. Pelitinib irreversibly binds covalently to epidermal growth factor receptors (EGFR) ErbB-1, -2 and -4, thereby inhibiting receptor phosphorylation and signal transduction and resulting in apoptosis and suppression of proliferation in tumor cells that overexpress these receptors.
Peptide sequence
N/A
CAS number
257933-82-7
Molecular weight
467.92
Category
Biochemicals
Other name
(E)-N-(4-(3-chloro-4-fluorophenylamino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide
Molecular formula
C₂₄H₂₃ClFN₅O₂
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (>10 mg/ml)
Storage condition
-20°C
Shipping condition
Gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
