NSC-23925 for cell activation
Catalog number
2686-5
Name
NSC-23925 for cell activation
Size
5 mg
Price
153.00 EUR
Supplier
Details
Description
NSC-23925 is a potent plasma membrane glycoprotein 1(Pgp1) inhibitor. It inhibits Pgp1 and reverses MDR1 (Pgp1) but does not inhibit MRP or BCRP-mediated MDR. NSC23925 directly inhibits the function of Pgp1 in a dose-dependent manner without altering the total expression level of Pgp1. NSC23925 stimulates ATPase activity of Pgp.
Peptide sequence
N/A
CAS number
858474-14-3
Molecular weight
421.36
Category
Biochemicals
Other name
2-(p-Methoxyphenyl)-α-2-piperidyl-4-quinolinemethanol dihydrochloride, NSC-23925, [2-(4-Methoxyphenyl)4-quinolinyl]-(piperidin-2-y)-methanol dihydrochloride
Molecular formula
C₂₂H₂₄N₂O₂ · 2HCl
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
H₂O (~5 mg/ml)
Storage condition
-20°C
Shipping condition
Gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
