NSC-87877 for cell activation
Catalog number
2687-50
Name
NSC-87877 for cell activation
Size
50 mg
Price
360.00 EUR
Supplier
Details
Description
NSC-87877 is a cell-permeable inhibitor of both SHP-1 and SHP-2 protein tyrosine phosphatases (IC₅₀ = 355 and 318 nM, respectively). It is much less effective against other protein tyrosine phosphatases and the dual-specificity phosphatase 26. Inhibits EGF-induced Erk1/2 activation in HEK293 cells and significantly reduces MDA-MB-468 cell viability/proliferation.
Peptide sequence
N/A
CAS number
56990-57-9
Molecular weight
459.45
Category
Biochemicals
Other name
8-Hydroxy-7-[(6-sulfo-2-naphthyl)azo]-5-quinolinesulfonic acid
Molecular formula
C₁₉H₁₃N₃O₇S₂
Physical appearance
Black solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
H₂O (~20 mg/ml) or DMSO (~ 5 mg/ml)
Storage condition
-20°C
Shipping condition
Gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
