CRANAD-2 for cell activation

GRANAD-2 is a near-infrared Aβ plaque-specific fluorescent probe penetrating the blood brain barrier and label senile plaques specifically in vivo. Upon interacting with Aβ aggregates, CRANAD-2 displays a 70-fold increase in fluorescence intensity accompanied by a 90 nm blue shift from 805 to 715 nm and a large increase in quantum yield. CRANAD -2 has been used to detect Aβ deposits noninvasively in vivo in transgenic Tg2576 mice.

N/A

1193447-34-5

410.26

Biochemicals

(T-4)-[(1E,6E)-1,7-Bis[4-(dimethylamino)phenyl]-1,6-heptadiene-3,5-dionato-kO3,kO5]difluoroboron

C₂₃H₂₅BF₂N₂O₂

Dark blue to black solid

N/A

No

Yes

≥98% by HPLC

DMSO (~ 2 mg/ml with slight warming)

-20°C

Gel pack

36 months

Protect from air and light

cell

For cells, cell lines and tissues in culture till half confluency.