Ponatinib for cell activation
Catalog number
2712-10
Name
Ponatinib for cell activation
Size
10 mg
Price
229.00 EUR
Supplier
Details
Description
Ponatinib is a multi-targeted tyrosine kinase inhibitor that is active against T315I and other BCR-Abl mutants. It inhibits all tested BCR-Abl mutants in cellular and biochemical assays, suppresses BCR-Abl(T315I)-driven tumor growth in mice, and completely abrogates resistance in cell-based mutagenesis screens.
Peptide sequence
N/A
CAS number
943319-70-8
Molecular weight
532.56
Category
Biochemicals
Other name
3-(2-Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-benzamide; AP24534
Molecular formula
C₂₉H₂₇F₃N₆O
Physical appearance
White solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (~50 mg/ml) or EtOH (~ 25 mg/ml)
Storage condition
-20°C
Shipping condition
Gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
