Mitomycin C for cell activation

Mitomycin C is an antitumor antibiotic isolated from Streptomyces sp. Mitomycin is activated by reduction in vivo generating oxygen radicals which produce crosslinks in DNA by alkylaion. This mechanism ultimately inhibits DNA synthesis which has a bacteriostatic effect. Mitomycin C has strong antitumor activity, especially against Ehrlich ascites tumor cells, and strong bactericidal action against gram-positive and gram-negative bacteria.

N/A

50-07-7

334.33

Biochemicals

[1aS-(1aα,8β,8aα,8bα)]-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione; Ametycine

C₁₅H₁₈N₄O₅

Bluish crystalline solid

N/A

No

No

Potency: ≥970 µg/mg

DMSO (~30 mg/ml) or H₂O (~2 mg/ml)

+4°C

Gel pack

36 months

Protect from air and light

cell

For cells, cell lines and tissues in culture till half confluency.