SGI-1027 for cell activation
Catalog number
2726-25
Name
SGI-1027 for cell activation
Size
25 mg
Price
588.00 EUR
Supplier
Details
Description
SGI-1027 is a selective DNA methyltransferase (DNMT) inhibitor. Inhibits DNMT1, DNMT3A, and DNMT3B with IC₅₀ values of 6, 8, and 7.5 µM, respectively. Treatment of different cancer cell lines with SGI-1027 results in selective degradation of DNMT1 with minimal or no effects on DNMT3A and DNMT3B
Peptide sequence
N/A
CAS number
1020149-73-8
Molecular weight
461.52
Category
Biochemicals
Other name
N-[4-[(2-Amino-6-methyl-4-pyrimidinyl)amino]phenyl]-4-(4-quinolinylamino)benzamide
Molecular formula
C₂₇H₂₃N₇O
Physical appearance
Off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
³98%
Reconstitute instructions
DMSO (~20 mg/ml)
Storage condition
-20°C
Shipping condition
Gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
