SirtACt for cell activation
Catalog number
2741-2
Name
SirtACt for cell activation
Size
2 mg
Price
153.00 EUR
Supplier
Details
Description
SirtAct is a potent Sirtuin 1 (SIRT1) activator. It increases fluorescence by 233% in a SIRT1 activity assay. SIRT1 stimulation by SirtAct leads to decreased tissue factor mediated thrombogenicity in mice. It inhibits NF-κB activation and reduces inflammatory cytokine production in lamina propria mononuclear cells from IBD patients. SirtAct also prevents and cures experimental colitis in a mouse model.
Peptide sequence
N/A
CAS number
839699-72-8
Molecular weight
367.5
Category
Biochemicals
Other name
2-Amino-N-cyclopentyl-1-(3-methoxypropyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide; CAY10591; SIRT1 activator 3; Sirtuin1 Activator 3
Molecular formula
C₂₀H₂₅N₅O₂
Physical appearance
Olive green solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by TLC
Reconstitute instructions
DMSO (50 mg/ml) or EtOH (20 mg/ml, warm)
Storage condition
-20°C
Shipping condition
Gel Pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
