Herbimycin A for cell activation
Catalog number
2748-100
Name
Herbimycin A for cell activation
Size
100 µg
Price
295.00 EUR
Supplier
Details
Description
Herbimycin A is an ansamycin antibiotic isolated from Streptomyces sp. Inhibits HSP90 and associated client proteins including v-Src, Bcr-Abl, Raf-1 and ErbB2. Herbimycin A reverts tyrosine kinase-induced oncogenic transformation without direct inhibition of phosphorylation activity. It also inhibits angiogenesis in a rat retinopathy model.
Peptide sequence
N/A
CAS number
70563-58-5
Molecular weight
574.70
Category
Biochemicals
Other name
(15R)-17-demethoxy-15-methoxy-11-O-methyl-geldanamycin
Molecular formula
C₃₀H₄₂N₂O₉
Physical appearance
Yellow lyophilized solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (~ 6 mg/ml)
Storage condition
-20°C
Shipping condition
Gel Pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
