2-Methyl-5-hydroxytryptamine hydrochloride for cell activation

2-Methyl-5-hydroxytryptamine is a 5-HT3 agonist (Ki = 1200 nM) and potent 5-HT6 ligand (Ki = 46 nM). Recently, this has been used as one of the components of the chemical cocktails used for reprogramming of mouse somatic cells toward pluripotent cells in the absence of Oct4.

N/A

845861-49-6

226.71

Biochemicals

3-(2-aminoethyl)-2-methyl-1H-indol-5-ol hydrochloride; 2-Me-5HT

C₁₁H₁₄N₂O.HCl

Beige solid

N/A

No

Y

≥98% by HPLC

H₂O (>20 mg/ml)

RT

RT

36 months

Protect from light and moisture

cell

For cells, cell lines and tissues in culture till half confluency.A methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms — CH3. In formulas, the group is often abbreviated Me. Such hydrocarbon groups occur in many organic compounds. It is a very stable group in most molecules. While the methyl group is usually part of a larger molecule, it can be found on its own in any of three forms anion, cation or radical. The anion has eight valence electrons, the radical seven and the cation six. All three forms are highly reactive and rarely observed,