VX-765 for cell activation
Catalog number
2781-5
Name
VX-765 for cell activation
Size
5 mg
Price
175.00 EUR
Supplier
Details
Description
VX-765 is a prodrug of VRT-043198, a potent and selective inhibitor of interleukin-converting enzyme/caspase-1 subfamily caspases. VRT-043198 displays 100- to 10,000-fold selectivity against caspase-3 and -6 to -9. Exhibits potent anti-inflammatory activities by inhibiting the release of IL-1β and IL-18.
Peptide sequence
N/A
CAS number
273404-37-8
Molecular weight
508.99
Category
Biochemicals
Other name
(2S)-1-[(2S)-2-[(4-amino-3-chlorobenzoyl)amino]-3,3-dimethylbutanoyl]-N-[(2R,3S)-2-ethoxy-5-oxooxolan-3-yl]pyrrolidine-2-carboxamide; Belnacasan
Molecular formula
C₂₄H₃₃ClN₄O₆
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Y
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (~ 200 mg/ml)
Storage condition
-20°C
Shipping condition
Gel Pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
