AZ10417808 for cell activation
Catalog number
2786-1
Name
AZ10417808 for cell activation
Size
1 mg
Price
132.00 EUR
Supplier
Details
Description
AZ10417808 is a selective non-peptide inhibitor of caspase-3 (Ki = 247 nM); displays > 40-fold selectivity over caspases 1, 2, 6, 7 and 8 (Ki > 10 μM). Completely blocks staurosporine-induced intracellular DEVDase activity in SH-SY5Y cells (IC₅₀ = 14.9 μM).
Peptide sequence
N/A
CAS number
331645-84-2
Molecular weight
434.23
Category
Biochemicals
Other name
2-(3,4-dichloroanilino)-6-nitro-4-oxo-N-prop-2-enyl-1H-quinazoline-8-carboxamide
Molecular formula
C₁₈H₁₃Cl₂N₅O₄
Physical appearance
Yellow solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Y
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (~ 10 mg/ml)
Storage condition
-20°C
Shipping condition
Gel Pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
