CO-1686 (Rociletinib) for cell activation

Catalog number
2794-25
Name
CO-1686 (Rociletinib) for cell activation
Size
25 mg
Price
675.00 EUR
Supplier

Details

Description
CO-1686 is an orally bioavailable, irreversible EGFR inhibitor, selectively targeting EGFRL858R/T790M mutant with a Ki value of 21 nM over Wt EGFR (Ki = 303 nM). Displays potent antineoplastic activities.
Peptide sequence
N/A
CAS number
1374640-70-6
Molecular weight
555.55
Category
Biochemicals
Other name
N-(3-((2-((4-(4-acetylpiperazin-1-yl)-2-methoxyphenyl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)amino)phenyl)acrylamide; AVL-301
Molecular formula
C₂₇H₂₈F₃N₇O₃
Physical appearance
White solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
y
Purification
≥98% by HPLC
Reconstitute instructions
DMSO
Storage condition
-20°C
Shipping condition
Gel Pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.