WS3 for cell activation

Catalog number
2799-5
Name
WS3 for cell activation
Size
5 mg
Price
153.00 EUR
Supplier

Details

Description
WS3 is a novel small molecule that promotes β cell proliferation with EC50 of 28 nM (induced R7T1 proliferation). More recently, WS3 has been found to mediate proliferation of primary retinal pigment epithelial cells. After WS3 removal, the retinal cells differentiated into a functional monolayer and remained functional in vivo, preserving vision when they were transplanted into RCS rats used as a model of retinal degeneration.
Peptide sequence
N/A
CAS number
1421227-52-2
Molecular weight
569.58
Category
Biochemicals
Other name
N-[6-[4-[[[[4-[(4-Methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-amino]carbonyl]amino]phenoxy]-4-pyrimidinyl]-cyclopropanecarboxamide, WS-3
Molecular formula
C₂₈H₃₀F₃N₇O₃
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Y
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (~ 10 mg/ml)
Storage condition
-20°C
Shipping condition
Gel Pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.