GSK-2118436 mesylate for cell activation
Catalog number
2800-5
Name
GSK-2118436 mesylate for cell activation
Size
5 mg
Price
142.00 EUR
Supplier
Details
Description
GSK2118436 is a selective BRAF V600E inhibitor. GSK2118436 binds to Raf family kinases and inhibits their activity. It is highly selective against B-Raf V600E with IC₅₀ of 0.8 nM, compared to wild type B-Raf and c-Raf with IC₅₀s of 3.2 nM and 5.0 nM, respectively.
Peptide sequence
N/A
CAS number
1195768-06-9
Molecular weight
615.67
Category
Biochemicals
Other name
N-[3-[5-(2-aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-4-yl]-2-fluorophenyl]-2,6-difluorobenzenesulfonamide, methanesulfonic acid; Dabrafenib Mesylate
Molecular formula
C₂₄H₂₄F₃N₅O₅S₃
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Y
Purification
≥98% by HPLC
Reconstitute instructions
DMSO
Storage condition
-20°C
Shipping condition
Gel Pack
Maximum time for storage
36 months
Storage instructions
Protect from air and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
