Smo agonist, SAG dihydrochloride for cell activation
Catalog number
2801-5
Name
Smo agonist, SAG dihydrochloride for cell activation
Size
5 mg
Price
751.00 EUR
Supplier
Details
Description
SAG hydrochloride is the water-soluble analog of SAG (Cat. No.1939). A cell-permeable Smoothened (Smo) agonist that has shown to induce Hedgehog pathway activation and counteract cyclopamine inhibition of Smo. SAG has been reported to act as an activator at low concentrations, but can inhibit Smo at very high concentrations.
Peptide sequence
N/A
CAS number
364590-63-6
Molecular weight
562.98
Category
Biochemicals
Other name
N-Methyl-N′-(3-pyridinylbenzyl)-N′-(3-chlorobenzo[b]thiophene-2-carbonyl)-1,4-diaminocyclohexane, dihydrochloride
Molecular formula
C₂₈H₂₈ClN₃OS. 2HCl
Physical appearance
Light yellow solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Y
Purification
≥98% by HPLC
Reconstitute instructions
H2O (~ 25 mg/ml) DMSO (~ 10 mg/ml)
Storage condition
-20°C
Shipping condition
Gel Pack
Maximum time for storage
36 months
Storage instructions
Protect from light and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
