VX-745 for cell activation
Catalog number
2812-25
Name
VX-745 for cell activation
Size
25 mg
Price
577.00 EUR
Supplier
Details
Description
VX-745 is a potent and selective inhibitor of p38α (IC₅₀ = 10 nM). It displays 22-fold greater selectivity versus p38β and no inhibition of p38γ. Also blocks TNFα production in LPS-stimulated HWB in vitro (IC₅₀ = 177 nM).
Peptide sequence
N/A
CAS number
209410-46-8
Molecular weight
436.26
Category
Biochemicals
Other name
5-(2,6-Dichlorophenyl)-2-((2,4-difluorophenyl)thio)-6H-pyrimido[1,6-b]pyridazin-6-one
Molecular formula
C₁₉H₉Cl₂F₂N₃OS
Physical appearance
Yellow solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (~40 mg/ml)
Storage condition
-20°C
Shipping condition
Gel Pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
