AMG-47a for cell activation
Catalog number
2825-5
Name
AMG-47a for cell activation
Size
5 mg
Price
229.00 EUR
Supplier
Details
Description
AMG-47a is a potent inhibitor of Lck and T cell proliferation. It exhibits anti-inflammatory activity (ED₅₀ = 11 mg/kg) in the anti-CD3 induced production of IL-2 in mice. In several other in vitro assays, AMG-47 displays subnanomolar inhibition against Lck, and low (
Peptide sequence
N/A
CAS number
882663-88-9
Molecular weight
535.56
Category
Biochemicals
Other name
4-Methyl-3-[2-[[2-(4-morpholinyl)ethyl]amino]-6-quinazolinyl]-N-[3-(trifluoromethyl)phenyl]benzamide
Molecular formula
C₂₉H₂₈F₃N₅O₂
Physical appearance
Beige solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO
Storage condition
-20°C
Shipping condition
Gel Pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
