2'-Deoxy-6-thioguanosine for cell activation
Catalog number
2828-25
Name
2'-Deoxy-6-thioguanosine for cell activation
Size
25 mg
Price
686.00 EUR
Supplier
Details
Description
6-Thio-dG induces telomere dysfunction in telomerase-positive human cancer cells and hTERT-expressing human fubroblasts, but not in telomerase-negative cells. Treatment with 6-thio-dG results in rapid cell death for a wide variety of cancer cells, whereas normal human fibroblasts and human colonic epithelial cells are mostly unaffected.
Peptide sequence
N/A
CAS number
789-61-7
Molecular weight
283.31
Category
Biochemicals
Other name
2'-Deoxy-6-thio-D-guanosine;6-Thio-2'-deoxyguanosine; 6-thio-DG
Molecular formula
C₁₀H₁₃N₅O₃S
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
M
Is it cell-permeable?
yes
Purification
≥97% by HPLC
Reconstitute instructions
DMSO:H₂O (1:2) (50 mM)
Storage condition
-20°C
Shipping condition
Gel Pack
Maximum time for storage
36 months
Storage instructions
Protect from air and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
