KRN-633 for cell activation
Catalog number
2839-5
Name
KRN-633 for cell activation
Size
5 mg
Price
153.00 EUR
Supplier
Details
Description
KRN-633 is a cell-permeable, reversible, and ATP-competitive inhibitor of VEGFR kinase activity (IC₅₀ values of 170 nM, 160 nM, and 125 nM for VEGFR-1, VEGFR-2, VEGFR-3, respectively). At higher concentrations KRN 633 inhibits PDGFR-α and c-KIT with IC₅₀ values of 0.97 and 4.3 μM, respectively, and is inactive towards a panel of 17 additional kinases.
Peptide sequence
N/A
CAS number
286370-15-8
Molecular weight
416.86
Category
Biochemicals
Other name
N-[2-chloro-4-[(6,7-dimethoxy-4-quinazolinyl)oxy]phenyl]-N'-propyl-urea
Molecular formula
C₂₀H₂₁ClN₄O₄
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (>8 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
