PD0332991 for cell activation
Catalog number
2843-25
Name
PD0332991 for cell activation
Size
25 mg
Price
458.00 EUR
Supplier
Details
Description
PD0332991 is a highly specific inhibitor of Cdk4 (IC₅₀ = 11 nM) and Cdk6 (IC₅₀ = 16 nM). Displays selectivity for Cdk4/6 over a panel of 34 additional protein kinases (IC₅₀ values are > 10 μM).
Peptide sequence
N/A
CAS number
571190-30-2
Molecular weight
447.53
Category
Biochemicals
Other name
6-Acetyl-8-cyclopentyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one, PD0332991, Palbociclib
Molecular formula
C₂₄H₂₉N₇O₂
Physical appearance
Light yellow to yellow solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
