SBE13 hydrochloride for cell activation
Catalog number
2847-10
Name
SBE13 hydrochloride for cell activation
Size
10 mg
Price
186.00 EUR
Supplier
Details
Description
SBE13 HCl is a potent and selective PLK1 (Polo-like kinase 1) inhibitor (IC₅₀ = 200 pM). Displays activity against PLK2 and PLK3 at higher concentrations (IC₅₀ values of 66 µM and 875 nM, respectively). Has no effect on Aurora kinase A.
Peptide sequence
N/A
CAS number
1052532-15-6
Molecular weight
479.4
Category
Biochemicals
Other name
N-[[4-[(6-Chloro-3-pyridinyl)methoxy]-3-methoxyphenyl]methyl]-3,4-dimethoxybenzeneethanamine hydrochloride
Molecular formula
C₂₄H₂₇ClN₂O₄.HCl
Physical appearance
White solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (>40 mg/ml) or H2O (~4 mg/ml with slight warming)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
