AMMC iodide for cell activation
Catalog number
2873-25
Name
AMMC iodide for cell activation
Size
25 mg
Price
1110.00 EUR
Supplier
Details
Description
AMMC iodide is a useful substrate for the human cytochrome P450 CYP2D6 isozyme. It is demethylated to the fluorescent product 3-[2-(N,N-diethyl-N-methyl ammonium)ethyl]-7-hydroxy-4-methylcoumarin (AMHC). After the AMMC is hydrolyzed, the pH is increased by addition of base for optimal fluorescence detection. AMMC has been used with human liver microsomes to determine CYP2D6 activity and inhibition.
Peptide sequence
N/A
CAS number
N/A
Molecular weight
431.31
Category
Biochemicals
Other name
3-[2-(N,N-diethyl-N-methylammonium)ethyl]-7-methoxy-4-methylcoumarin iodide
Molecular formula
C₁₈H₂₆INO₃
Physical appearance
Off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
No
Purification
≥98% by NMR
Reconstitute instructions
Acetonitrile
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
