ANA-12 for cell activation
Catalog number
2878-10
Name
ANA-12 for cell activation
Size
10 mg
Price
197.00 EUR
Supplier
Details
Description
ANA-12 is a potent and selective TrkB antagonist that prevents activation of the receptor by BDNF with a high potency. It binds selectively to TrkB and inhibits processes downstream of TrkB without altering TrkA and TrkC functions. In adult mice model ANA-12 decreases TrkB activity in the brain without affecting neuronal survival. Displays antidepressant properties.
Peptide sequence
N/A
CAS number
219766-25-3
Molecular weight
407.49
Category
Biochemicals
Other name
N-[2-[[(Hexahydro-2-oxo-1H-azepin-3-yl)amino]carbonyl]phenyl]benzo[b]thiophene-2-carboxamide
Molecular formula
C₂₂H₂₁N₃O₃S
Physical appearance
White solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (>20 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
