AG-014699 phosphate for cell activation

Catalog number
2890-5
Name
AG-014699 phosphate for cell activation
Size
5 mg
Price
371.00 EUR
Supplier

Details

Description
AG-014699 phosphate is a potent, cell-permeable inhibitor of PARP1 with Ki of 1.4 nM.  It selectively binds to PARP 1 and inhibits the PARP1-mediated DNA repair, thus potentiating the genomic instability and apoptosis. Displays antineoplastic activity.
Peptide sequence
N/A
CAS number
459868-92-9
Molecular weight
421.36
Category
Biochemicals
Other name
8-Fluoro-2-(4-((methylamino)methyl)phenyl)-4,5-dihydro-1H-azepino[5,4,3-cd]indol-6(3H)-one phosphate; Rucaparib; PF-01367338
Molecular formula
C₁₉H₂₁FN₃O₅P
Physical appearance
Light yellow to yellow solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (~20 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.