Regorafenib for cell activation
Catalog number
2891-25
Name
Regorafenib for cell activation
Size
25 mg
Price
588.00 EUR
Supplier
Details
Description
Regorafenib is a multi-kinase inhibitor targeting angiogenic (VEGFR, TIE-2), stromal (PDGFR-β) and oncogenic (RAF, RET and c-KIT) receptor tyrosine kinases, with IC₅₀s of 17, 40 and 69 nM for c-KIT, VEGFR2, B-Raf, respectively. Displays potential antiangiogenic and antineoplastic activities.
Peptide sequence
N/A
CAS number
755037-03-7
Molecular weight
482.81
Category
Biochemicals
Other name
4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-N-methylpicolinamide; BAY 73-4506
Molecular formula
C₂₁H₁₅ClF₄N₄O₃
Physical appearance
Off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (>50 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
