LDE-225 for cell activation
Catalog number
2892-25
Name
LDE-225 for cell activation
Size
25 mg
Price
588.00 EUR
Supplier
Details
Description
LDE225 is a potent and selective antagonist of Smoothened (Smo) with IC₅₀ values of 2.5 nM and 1.3 nM for human and mouse Hedgehog, respectively. LDE-225 induces dose-related inhibition of Hh and Smo-dependent tumour growth.
Peptide sequence
N/A
CAS number
956697-53-3
Molecular weight
485.5
Category
Biochemicals
Other name
N-(6-((2R,6S)-2,6-dimethylmorpholino)pyridin-3-yl)-2-methyl-4'-(trifluoromethoxy)-[1,1'-biphenyl]-3-carboxamide; Sonidegib; Erismodegib; NVP-LDE225
Molecular formula
C₂₆H₂₆F₃N₃O₃
Physical appearance
Off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (~5 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
