Caffeine for cell activation
Catalog number
2914-5G
Name
Caffeine for cell activation
Size
5 g
Price
121.00 EUR
Supplier
Details
Description
Caffeine is a popular central nervous system (CNS) stimulant. It is a well-studied substrate of Cytochrome P450 enzymes like CYP1A2. Caffeine is taken up by transporters at the blood brain barrier. Its stimulating effects are believed to act through adenosine receptors and monoamine neurotransmitters. It is an adenosine receptor antagonist and adenosine 3',5'-cyclic monophosphate (cAMP) phosphodiesterase inhibitor. It can affect cellular calcium levels, releasing calcium from cellular stores. It has been shown to inhibit cellular DNA repair mechanisms.
Peptide sequence
N/A
CAS number
58-08-2
Molecular weight
194.2
Category
CYP substrate, Biochemicals
Other name
1,3,7-trimethylxanthine, Methyltheobromine, 3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione
Molecular formula
C₈H₁₀N₄O₂
Physical appearance
White powder
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥99% by HPLC
Reconstitute instructions
Water (~16 mg/ml), Ethanol (~15 mg/ml)
Storage condition
RT
Shipping condition
gel pack
Maximum time for storage
48 months
Storage instructions
Protect from air, light and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
