PTC-124 for cell activation
Catalog number
9421-10
Name
PTC-124 for cell activation
Size
10 mg
Price
142.00 EUR
Supplier
Details
Description
PTC-124 has been reported to help the ribosome skip over the premature stop, restore production of functional protein, and thereby potentially treat these genetic diseases. In a mouse model of cystic fibrosis caused by nonsense mutations, PTC-124 treatment has been shown to restore cystic fibrosis transmembrane conductance regulator (CFTR) protein expression and function.
Peptide sequence
N/A
CAS number
775304-57-9
Molecular weight
284.24
Category
Biochemicals
Other name
3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]-benzoic acid
Molecular formula
C₁₅H₉FN₂O₃
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (~50 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
