SR1664 for cell activation
Catalog number
9432-5
Name
SR1664 for cell activation
Size
5 mg
Price
327.00 EUR
Supplier
Details
Description
SR1664 blocks phosphorylation of peroxisome proliferator-activated receptor γ (PPARγ) by cyclin-dependent kinase 5 with an IC₅₀ value of 80 nM (Ki = 28.7 nM) without displaying agonist activity at the PPARγ receptor. It demonstrates potent, dose-dependent anti-diabetic effects in obese mice without inducing fluid retention and weight gain or inhibiting bone formation.
Peptide sequence
N/A
CAS number
1338259-05-4
Molecular weight
547.6
Category
Biochemicals
Other name
4'-[[2,3-Dimethyl-5-[[[(1S)-1-(4-nitrophenyl)ethyl]amino]carbonyl]-1H-indol-1-yl]methyl]-[1,1'-biphenyl]-2-carboxylic acid
Molecular formula
C₃₃H₂₉N₃O₅
Physical appearance
Yellow solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98%
Reconstitute instructions
DMSO (>40 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
