TAE-226 for cell activation
Catalog number
9436-25
Name
TAE-226 for cell activation
Size
25 mg
Price
675.00 EUR
Supplier
Details
Description
TAE-226 is a potent ATP-competitive inhibitor of FAK and IGF-IR with potential anticancer activity. TAE-226 can block FAK and IGF-IR signaling pathways. TAE-226 inhibits the phosphorylation of FAK as well as the downstream effectors AKT, extracellular signal-related kinase, and S6 ribosomal protein in multiple glioma cell lines.
Peptide sequence
N/A
CAS number
761437-28-9
Molecular weight
468.94
Category
Biochemicals
Other name
2-((5-chloro-2-((2-methoxy-4-morpholinophenyl)amino)pyrimidin-4-yl)amino)-N-methylbenzamide; NVP-TAE226
Molecular formula
C₂₃H₂₅ClN₆O₃
Physical appearance
Crystalline solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (>5 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
